PoreIQExfoliants & acne · Acne actives
Benzoyl Peroxide
An over-the-counter acne ingredient that reduces acne-causing bacteria on the skin.
- Also listed as
- BPO
- Best for
- Acne-prone skin · Body breakouts (as a wash)
- When to use
- AM/PM
- Pairings
- 4 combinations checked
What it is
Benzoyl peroxide releases oxygen in the pore, which helps reduce the bacteria involved in breakouts. It is widely available in cleansers and spot treatments, from 2.5% to 10%.
Benefits
- Helps with inflamed breakouts
- Works quickly on spots
- Available without a prescription in the US
Watch-outs
- Bleaches towels, pillowcases and clothing
- Dryness and peeling are common
- Higher strength is not always more effective, but is more irritating
How to use it
Start with 2.5–5%, once a day, as a short-contact wash or thin layer. Moisturize afterwards. For persistent or painful acne, see a dermatologist.
Can you mix benzoyl peroxide with…
- Benzoyl Peroxide + RetinolUse at different timesBenzoyl peroxide can break down some retinoids, and both are drying.
- Benzoyl Peroxide + Vitamin CUse at different timesBenzoyl peroxide is an oxidizer and can reduce the effectiveness of vitamin C.
- Benzoyl Peroxide + Salicylic AcidUse with cautionBoth are common acne actives and both are drying.
- Benzoyl Peroxide + NiacinamideWorks well togetherNiacinamide can help with the dryness and redness that benzoyl peroxide may cause.
Frequently asked questions
What does benzoyl peroxide do for skin?
An over-the-counter acne ingredient that reduces acne-causing bacteria on the skin.
Can I use benzoyl peroxide and retinol together?
Some older retinoids can be broken down by benzoyl peroxide, so many people use benzoyl peroxide in the morning and the retinoid at night.
Similar ingredients
General cosmetic information, reviewed against public guidance such as the American Academy of Dermatology. Patch test new products. For medical concerns, see a dermatologist. Last updated 2026-10-22.